A Non-drug Vitamin + Mineral
Nicomide® is formulated to address the specific nutritional deficiencies that are associated with skin irritation and inflammation.1-12
Nicomide® provides key nutrients that may help to better moderate the cellular processes that lead to dermal irritation and inflammation.1-12
Niacinamide and zinc in Nicomide® may help moderate inflammatory acne by the following mechanisms:
- Inhibit leukocytic chemotaxis1-8
- Inhibit lysosomal enzyme release1-9
- Inhibit lymphocytic transformation1,3-5
- Inhibit mast cell degranulation1,3-5,9-11
- Inhibit P. acnes lipase activity1,8,10,12
Nicomide® is a non-drug vitamin and mineral dietary supplement offered in an easy-to-take oral tablet.
THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE. CLICK HERE
FOR IMPORTANT SAFETY INFORMATION.
contains non-branded L-methylfolate vs. ingredients supplied by branded manufacturers. The L-methylfolate ((6S)-N5-methyltetrahydrofolic acid calcium salt) in Nicomide®
is less than 1.0% D-isomer.
REFERENCES: 1. Wolverton, S, Comprehensive Dermatologic Drug Therapy Edinburgh, London, New York, Oxford, Philadelphia, St Louis,
Sydney, Toronto 2013 : 3rd ed, Vol 2013. 2. Fivenson, D, ‘The Mechanism of Action of Nicotinamide and Zinc in Inflammatory
Skin Diseases’, 77 ( 1S ): Cutis. 2006; 5 – 10. 3. Niren, N , ‘Pharmacologic Doses of Nicotinamide in the Treatment of
Inflammatory Skin Conditions A Review’, 77 ( 1S ): Cutis. 2006; 11 – 16. 4. Namazi, M, ‘Nicotinamide: a potential addition to the
anti-psoriatic weaponry’, 17 (11): The FASEB Journal - Federation of American Societies for Experimental Biology. 2003;
1377 – 1379. 5. Shalita A, Smith G, Parish L, Sofman M, Chalker D ‘Topical Nicotinamide Compared with Clindamycin Gel in
the Treatment of Inflammatory Acne Vulgaris’, 34( 6 ): International Journal of Dermatology.1995; 434 - 437. 6. Dreno, B ,
Amblard P, Agache P ‘Low Doses of Zinc Gluconate for Inflammatory Acne’, 6 ( 69 ): Acta Derm Venerol. 1989; 541 – 543.
7. Cunliffe, W , Burke B, Dodman B ‘A double-blind trial of a zinc sulphate/citrate complex and tetracycline in the treatment
of acne vulgaris’, 101 ( 3 ): British Journal of Dermatology.1979; 321 – 325. 8. Cassano, N, Amoruso A, Vena GA ‘Zinc Nutritive
and Skin: An Overview’ , 20 ( ): Journal of Applied Cosmetol. 2002; 183 – 193. 9. Berk, M , Lorinez A ‘The Treatment of Bullous
Pemphigoid With Tetracycline and Niacinamide’, 122 ( ): Archives Dermatology. 1986; 670 – 674. 10. Schwartz, J , Marsh R,
Draelos Z ‘Zinc and Skin Health: Overview of Physiology and Pharmacology’, 31 ( 7 ): Dermatol Surg. 2005; 837 – 847.
11. Michaelsson, A , Juhiln L, Vahlquist A ‘Effects of Oral Zinc and Vitamin A in Acne’, 113 (1): Arch Dermatol. 1977; 31 – 36.
12. Higaki, S , ‘Lipase Inhibitors for the treatment of acne’, 22 ( ): Journal of Molecular Catalysis B Enzymatic. 2003; 377 – 384.
NO COUPON REQUIRED
No More Than
$25 Per Fill*
*Most eligible patients will pay no more than $25 for each fill. For Nicomide® the maximum benefit is $100 per fill. Patient will be responsible for any additional money due.