nicomide® helps smooth the bumps associated with inflammation

genPicNicomide® can help moderate skin redness, swelling and irritation associated with inflammatory acne.

Supplementing nutritional intake with Nicomide®’s scientifically formulated balance of vitamins and minerals can help provide multiple mechanisms to help support a patient in their struggle with inflammatory acne.

Nicomide®'s proprietary blend of Niacinamide, Zinc, Folic Acid (as L-methylfolate calcium) and Copper can work in combination to aid in moderating the inflammatory response to minimize inflammatory acne lesions and addressing the body’s response before noncystic acne forms.1-12

By adding Nicomide®  to your regimen, you have a new angle of attack against inflammatory acne.

THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE. CLICK HERE FOR IMPORTANT SAFETY INFORMATION.

Nicomide® contains non-branded L-methylfolate vs. ingredients supplied by branded manufacturers. The L-methylfolate ((6S)-N5-methyltetrahydrofolic acid calcium salt) in Nicomide® is less than 1.0% D-isomer.
REFERENCES 
1. Wolverton, S, Comprehensive Dermatologic Drug Therapy Edinburgh, London, New York, Oxford, Philadelphia, St Louis, Sydney, Toronto 2013 : 3rd ed, Vol 2013. 2. Fivenson, D, ‘The Mechanism of Action of Nicotinamide and Zinc in Inflammatory Skin Diseases’, 77 ( 1S ): Cutis 2006; 5 – 10 3. Niren, N , ‘Pharmacologic Doses of Nicotinamide in the Treatment of Inflammatory Skin Conditions A Review’, 77 ( 1S ): Cutis 2006; 11 – 16 4. Namazi, M, ‘Nicotinamide: a potential addition to the anti-psoriatic weaponry’, 17 (11): The FASEB Journal - Federation of American Societies for Experimental Biology 2003; 1377 – 1379 5. Shalita A, Smith G, Parish L, Sofman M, Chalker D ‘Topical Nicotinamide Compared with Clindamycin Gel in the Treatment of Inflammatory Acne Vulgaris’, 34( 6 ): International Journal of Dermatology1995; 434 - 437 6. Dreno, B , Amblard P, Agache P ‘Low Doses of Zinc Gluconate for Inflammatory Acne’, 6 ( 69 ): Acta Derm Venerol 1989; 541 – 543 7. Cunliffe, W , Burke B, Dodman B ‘A double-blind trial of a zinc sulphate/citrate complex and tetracycline in the treatment of acne vulgaris’, 101 ( 3 ): British Journal of Dermatology1979; 321 – 325 8. Cassano, N, Amoruso A, Vena GA ‘Zinc Nutritive and Skin: An Overview’ , 20 ( ): Journal of Applied Cosmetol 2002; 183 – 193 9. Berk, M , Lorinez A ‘The Treatment of Bullous Pemphigoid With Tetracycline and Niacinamide’, 122 ( ): Archives Dermatology 1986; 670 – 674 10. Schwartz, J , Marsh R, Draelos Z ‘Zinc and Skin Health: Overview of Physiology and Pharmacology’, 31 ( 7 ): Dermatol Surg 2005; 837 – 847 11. Michaelsson, A , Juhiln L, Vahlquist A ‘Effects of Oral Zinc and Vitamin A in Acne’, 113 (1): Arch Dermatol 1977; 31 – 36 12. Higaki, S , ‘Lipase Inhibitors for the treatment of acne’, 22 ( ): Journal of Molecular Catalysis B Enzymatic 2003; 377 – 384

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